Sterile Connection, Diaphragm Seals
Description
Diaphragm seals are used to protect the pressure measuring instrument from aggressive, adhesive, crystallising, corrosive, highly viscous, environmentally hazardous or toxic media. A diaphragm made of the appropriate material provides for the separation from the medium to be measured. Thus even the most difficult measuring requirements can be met by combining measuring instruments with diaphragm seals.
A fluid inside the system, which can be chosen to suit the particular application, hydraulically transmits the pressure to the measuring instrument.
Almost limitless application possibilities exist due to the large number of available variants, such as diaphragm seal designs or materials. The type of process connection (flange, threaded and sterile connection) and the basic method of manufacture are important design differentiation criteria.
For further technical information on diaphragm seals and diaphragm seal systems see IN 00.06 'Application, operating principle, designs'.
for further approvals see page 3
Diaphragm seal with sterile connection, model 990.60
The model 990.60 diaphragm seal with NEUMO BioControl ® connection is particularly suited for use in sterile processes and is adapted to the process via the NEUMO BioControl ® housing. This enables a hygienic integration of measuring instruments into pipelines or, by means of block flanges, into tanks or fermenters.
The diaphragm seal systems can withstand the cleaning vapour temperatures occurring in the SIP processes and thus ensure a sterile connection between the medium to be measured and the diaphragm seal.
Assembly of the diaphragm seal and measuring instrument is made via a direct assembly as standard or optionally via a cooling element or a flexible capillary.
Special features
- Dead space free
- Hygienic design
- Materials and surface finish qualities in accordance with pharmaceutical industry directives and standards 3-A compliant
| Model | 990.60 |
| Product family | 990 |
| Subcategory | Diaphragm seal |
| Pressure ranges | 0…16 bar · 0…25 bar · 0…0.25 bar |
| Process connection | NEUMO BioControl® connectionNEUMO BioControl® |
| Case material | Stainless steel 1.4435 (316L), Stainless steel 1.4539 (904L), Hastelloy C276 (2.4819), Stainless steel 1.4435 (316L), electropolished |
| Wetted parts material | Stainless steel 1.4435 (316L), Stainless steel 1.4539 (904L), Hastelloy C276 (2.4819), Stainless steel 1.4435 (316L), electropolished |
| Sealing material | EPDM, FEP with FPM core |
| Weight | 0.27 kg |
| Certifications | EACCRN3-A |
| Datasheet languages | EN, DE |
| Upper body | Wetted part Diaphragm |
|---|---|
| Standard | |
| Stainless steel 1.4435 (316L) | Stainless steel 1.4435 (316L) |
| Option | |
| Stainless steel 1.4435 (316L), electropolished | Stainless steel 1.4435 (316L), electropolished 1) |
| Stainless steel 1.4539 (904L) | Stainless steel 1.4539 (904L) |
| Hastelloy C276 (2.4819) | Hastelloy C276 (2.4819) |
| BioControl ® | Dimensions inmm | Weight | ||||||
|---|---|---|---|---|---|---|---|---|
| connection | Mb | d 2 | d 4 | D | f | b | k | in kg |
| Size 25 | 22 | 4xØ7 | 30.5 | 64 | 11 | 20 | 50 | 0.27 |
| Size 50 | 40 | 4xØ9 | 50 | 90 | 17 | 27 | 70 | 0.65 |
| Size 65 | 59 | 4 x Ø11 | 68 | 120 | 17 | 27 | 95 | 1.30 |
| Size 80 | 72 | 4 x Ø11 | 87.5 | 140 | 25 | 37 | 115 | 2.65 |
| Material | Unified numbering system (UNS) |
|---|---|
| Stainless steel 316L (1.4404 or 1.4435) | S31603 |
| Stainless steel 904L (1.4539) | N08904 |
| Stainless steel 321 (1.4541) | S32100 |
| Stainless steel 316Ti (1.4571) | S31635 |
| Stainless steel 1.4466 (urea grade) | S31050 |
| Duplex 2205 (1.4462) | S31803 |
| Superduplex 1.4410 | S32750 |
| Tantalum (also lining) | R05200 |
| Hastelloy C276 (2.4819) | N01276 |
| Hastelloy C22 (2.4602) | N06022 |
| Inconel 600 (2.4816) | N06600 |
| Incoloy 825 (2.4858) | N08825 |
| Inconel 625 (2.485) | N06625 |
| Monel 400 (2.4360) | N04400 |
| Nickel 200 (2.4066) | N02200 |
| Nickel 201 (2.4068) | N02201 |
| Titanium 3.7035 (class 2) | R50400 |
| Titanium 3.7235 (class 7) | R52400 |
| Zirconium GR702 | R60702 |
| Designation | Identi- fication number | Solidi- fication point | Boiling/ degradation point | Density at 25 °C | Kin.Viscosity at 25 °C | Remark |
|---|---|---|---|---|---|---|
| KN | °C | °C | g/cm³ | cSt | ||
| Silicone oil | 2 | -45 | +300 | 0.96 | 54.5 | Universal application |
| Glycerine | 7 | -35 | +240 | 1.26 | 759.6 | FDA 21 CFR 182.1320 |
| Silicone oil | 17 | -90 | +200 | 0.92 | 4.4 | Low temperatures |
| Halocarbon | 21 | -60 | +175 | 1.89 | 10.6 | Oxygen 1) and chlorine |
| Methylcyclopentane | 30 | -130 | +60 | 0.74 | 0.7 | For very low temperatures |
| High-temperature silicone oil | 32 | -25 | +400 | 1.06 | 47.1 | For high temperatures |
| Neobee® M-20 | 59 | -35 | +260 | 0.92 | 10.0 | FDA 21 CFR 172.856, 21 CFR 174.5 |
| DI water | 64 | +4 | +85 | 1.00 | 0.9 | For ultrapure media |
| Silicone oil | 68 | -75 | +250 | 0.93 | 10.3 | |
| DI water/propanol mixture | 75 | -30 | +60 | 0.92 | 3.6 | For ultrapure media |
| Medicinal white mineral oil | 92 | -15 | +260 | 0.85 | 45.3 | FDA 21 CFR 172.878, 21 CFR 178.3620(a); USP, EP, SP |
View all (5)
| Maximum temperature | Maximum oxygen pressure |
|---|---|
| to 60 °C | 50 bar |
| > 60 °C to 100 °C | 30 bar |
| > 100 °C to 175 °C | 25 bar |
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